Most migraine medications are pills that need to be taken daily. Emgality is different because it is an injection that can be administered monthly at home with a prefilled pen or syringe.
Your doctor will teach you how to administer the injection. Be sure to read the Instructions for Use.
1. Reduces pain
Emgality helps prevent migraine and cluster headaches by blocking the activity of a protein in your body called calcitonin gene-related peptide. It also reduces the frequency of your attacks by interrupting the cycle of pain-triggering chemicals in your brain.
Emgality is an injection that your doctor gives you under the skin. Your doctor may administer your first dose (loading dose) at their office or you might be taught how to do it yourself at home.
During clinical studies, it was found that patients who received monthly injections saw a reduction in the number of days with migraine pain compared to placebo.
During the treatment process, be sure to tell your doctor about any other medications or supplements you are taking. This includes prescription and over-the-counter medicines, vitamins, herbs, and supplements. Emgality is a monoclonal antibody, which generally doesn’t interact with other medications or cause harmful side effects.
2. Reduces nausea
Before starting to take Emgality, you should consult your doctor about its possible side effects. This is to help them decide if it’s safe for you, and how much to take each month. You should also tell them about any other health conditions you have and any medications or supplements you take, whether routine or occasional.
During the first visit, your doctor will show you how to inject the medication, either using a prefilled syringe or injection pen. They may administer the first dose (loading dose) at their office, but you can give yourself subsequent injections at home. Ensure you choose an injection area that is free of irritation and bruising, such as your abdomen or thigh. It’s important not to rub the injection site, as this can cause pain and itching.
3. Reduces vomiting
Emgality works by blocking the activity of a protein in your body called CGRP, which is involved in inflammation and vasodilation (widening of blood vessels). Unlike most drugs that target multiple chemicals or parts of cells, monoclonal antibodies like Emgality only target a single substance in the body.
This medication is only available with a prescription from your doctor. You will receive it in either a pen or prefilled syringe. Each pen or syringe contains a single dose of medicine that is meant to be used once and then discarded.
It’s not known if Emgality passes into human breast milk. If you are breastfeeding, talk to your doctor before taking this medication. In three studies, side effects of Emgality were generally mild and went away within one to two days (1, 2, 3). If you have serious or life-threatening side effects, call your doctor right away.
4. Reduces fatigue
Fatigue is a common side effect of migraine and cluster headache. It’s important to be aware of the symptoms so you can report them to your doctor right away.
Mild side effects of Emgality are usually not severe and go away within a few days or a couple of weeks. But you should call your doctor or the emergency number if you have serious side effects such as:
You can inject Emgality into your abdomen, thigh, or upper arm using an injection pen or prefilled syringe. A medical professional will show you how to do this before you start treatment. You should also know that each prefilled syringe or injection pen is for one use only, so throw it away after you inject your dose.
5. Reduces dizziness
Emgality is used as a preventative treatment for migraine, which is a recurring condition characterized by moderate to severe throbbing or pulsing head pain. It can also cause other symptoms such as nausea, vomiting, sensitivity to light and sound, and a runny nose on one side of the face. It can also be used to treat episodic cluster headaches, which are sudden, severe, and recurrent.
Emgality is administered as an injection under the skin, usually in your abdomen, thigh, or upper arm. Your doctor or a nurse will teach you how to administer the medication safely. You can ask a family member or friend to help you if needed.
Some medicines may interfere with Emgality, so tell your doctor about all the drugs and supplements you take. This includes prescription and over-the-counter medications, as well as vitamins and herbal remedies.